Look Inside New Lewis Drug, Sanford Health In Downtown Sioux Falls

Your Money Matters

An opening date has been set for the new Lewis Drug and Sanford Health clinic in downtown Sioux Falls.  

You can start seeing doctors, along with getting medication, groceries and other essentials on August 30. 

This is a monumental moment for the growing downtown community.

For the first time in decades, downtown Sioux Falls will have a pharmacy and clinic. Crews are busy putting the finishing touches on the new Lewis Drug and Sanford Health building.

“The selection here is going to be a little bit different than your standard Lewis store because we’re working with a smaller footprint. It’s 5,500 square feet,” Lewis Drug Corporate Vice President Nikki Griffin said.

Griffin says there will be a wide variety of items from fresh Flyboy Donuts to frizz control.

“The home essentials, the houseware, the hardware, the cosmetics,” Griffin said.

The store also has unique architecture with a mix of old and new, including reclaimed barn wood and old photos from Lewis’ first location that opened downtown in 1942.

“We have retro striped awning, which we used to have. It’s very much the 40s and 50s aesthetic,” Griffin said.

You’ll find a Sanford Health clinic at the back of the building. No appointment will be necessary. You simply walk in.

“Convenience is very important. This generation of young people are more interested in getting their care right away, right now,” Sanford Health Dr. Brian Tjarks said.

Even though this clinic is small at just 850 square feet, it will have X-ray and lab capabilities.

“It’s really the first clinic in downtown Sioux Falls that has the ability to provide acute care for people who work here, live here and visit here,” Tjarks said.

New services in the up-and-coming area of downtown Sioux Falls.

“We can be that one-stop shop,” Griffin said.

The next door restaurant and bar, PAve, also has a patio on top of the Lewis-Sanford building. 

Here are Lewis’ hours:
Monday-Friday: 7:30 a.m.-8:00 p.m. 
Saturday: 9:00 a.m.-7:00 p.m.
Sunday: 11:00 a.m.-4:00 p.m.

Here are Sanford’s hours: 
Monday-Friday: 8:00 a.m.-7:00 p.m.
Saturday: 9:00 a.m.-5:00 p.m.
Sunday: Closed

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