User uShare Login | Register

Along with posting photos, videos, and stories, your uShare account lets you post Classified Ads, recipes on What's For Dinner, and Announcements.

61° View Weather Current Conditions Sioux Falls Change Location
Set Weather Options



Share your Photos, Videos, and Stories on uShare! Click here to get started.


[0] My Saved Articles
Back to all news


Find local businesses
on the KELO Pages!


Gender Equality In Research

February 10, 2014, 6:17 PM by Casey Wonnenberg

Gender Equality In Research

If you and your spouse take the same medication, the drug's reaction could be much different in your body than a person of the opposite sex.

A recent report on "60 Minutes" used the sleep aid Ambien as an example. Researchers found it can be much more potent in women.

From cancer to type one diabetes, Sanford researchers are studying many different diseases. For each trial, they aim to get the same number of male and female participants. Decades ago that wasn't the case. Clinical trials were made up of mostly men.

Any clinical study now has to go through an institutional review. One of the things considered is gender equality.

"If you don't have gender balance, you need to explain why. That may be because at that point you already know maybe the drug is going to be metabolized differently or if it's in women of potentially birthing age, you have to be very careful," Vice President of Sanford Research David Pearce said.

However, most projects don't have gender equality in the pre-clinical stage before a drug is tested in humans. That's because it's best not to mix female and male mice.

“It’s easier to work with male mice because tracking the estrus cycle in female mice is somewhat difficult. That will truly influence the way some of the drugs are metabolized," Pearce said.

After getting results, researchers can put all the information from both sexes together or they can separate it by a specific category, like gender, to find trends.

"We're finding more and more that the interactions of those particular genes are different in men and women," Pearce said.

Which is why Pearce says researchers are focusing more on an individual's DNA and how that relates to drug metabolism. This will hopefully prevent over and under medicating patients.

Not only do women now play a larger role in clinical trials, but more women are choosing the research field, especially locally. At Sanford 50 percent of research staff are women. Nationwide, that statistic is 15 percent.

Previous Story

Next Story


Find Local Businesses on KELO Pages!

View healthbeat

You may also like

Local Doctors Create Headache Treatment

4/15/2014 6:22 PM

Millions of Americans suffer from chronic, severe headaches on a regular basis.  Local doctors have now teamed up to create technology to diagnos...

Full Story | Watch
Increase In Whooping Cough & STDs In SD

4/17/2014 10:41 AM

The number of whooping cough cases appears to be on the rise in South Dakota.

Full Story
OB Care In Small Towns

4/16/2014 6:39 PM

While a growing number of doctors at small-town hospitals are no longer able to deliver babies, Sioux Center Health is building a new birthing center.

Full Story | Watch
Increase In Child Abuse Reports

4/17/2014 6:23 PM

A KELOLAND mom is spreading awareness about child abuse after her son suffered from shaken baby syndrome.

Full Story | Watch
Testing For Allergies That Affect Eyes

4/14/2014 6:13 PM

If your eyes are itchy and watery lately, you could already be battling spring allergies.  But it can be difficult to tell whether you're suf...

Full Story | Watch


KELOLAND TV: 501 S. Phillips Avenue, Sioux Falls, SD 57104
Phone: 605.336.1100 · Breaking News call: 1-800-888-5356
Web Site Design and Custom Programming By: Lawrence & Schiller© 2014 KELO-TV -- KELOLAND.COM -- ALL RIGHTS RESERVED