A crash Wednesday morning near Mellette killed four men and sent two others to the hospital.
Authorities say an SUV, carrying five men from Michigan, didn't stop at the junction of US Highway 281 and SD Highway 20.
It was hit by a semi truck.
The collision killed four men in the SUV and sent a fifth passenger to the hospital with life-threatening injuries.
The truck driver, from North Dakota, is expected to be okay.