Orange City Police Chief Jim Pottebaum says the three-year-old child in the day care abuse case died on Thursday around 5:40 p.m. in the hospital.
The child was hospitalized with severe head injuries, including a skull fracture and brain trauma on Tuesday.
33-year-old Rochelle Lynn Sapp is charged with willful injury and child endangerment resulting in serious injury.
The Orange City Police Department is waiting for the autopsy report on the child before they press new charges against Sapp.
Police say Sapp admitted to throwing the child to the floor during an interview with them on Wednesday.
Sapp was arrested Thursday in Orange City and is currently out of jail on bond.