Registration is at 11 am at J & L Harley Davidson.
Ride stops include Luverne, MN, Rock Rapids, IA and Canton.
Rides are also starting today in Vermillion, Mitchell and Madison.
Another CMN fundraiser is "Pink My Ride."
The annual car show and dine out will be held from 11 am to 3 pm at Thunder Road in Sioux Falls.
That's followed by the races at I-90 Speedway in Hartford.
Terrace Manor in Dell Rapids is hosting a rummage/bake sale and ice cream social today.
It's a fundraiser for the family of Kimberly Swenson, who's daughter Kenaniah is battling kidney and heart problems.
The activities go from 9 am to 1 pm.
Grammy Award-winning trumpeter Phil Driscoll will perform tonight at Faith Family Church in Sioux Falls.
His performance is at seven, following by two Sunday performances at 10 am and 7 pm.
The Sioux Valley Model Engineers Society is hosting an open house today at the W-H Lyon Fairgrounds.
It's at the society's clubhouse building near the fairgrounds north gate.
The open house is from 10 am to 5 pm.
Director of Parks and Recreation Don Kearney will answer questions from the public today at Mayor Mike Huether's Listening and Learning Session.
It's at the Whisk & Chop Cafe in downtown Sioux Falls from 9-10:30 am.
Huether will not be attending today because of a family obligation
Another season of Moonlight Movies kicks off in downtown Sioux Falls.
Tonight's free movie at Fawick Park is Tale of Despereaux.
It gets underway at dusk.
The Sioux Falls Fighting Pheasants baseball team takes on Sioux City tonight.
First pitch is at 7:05 at Sioux Falls Stadium.
Tickets go from $6-$10.
The Bikes & Babes Rally For Miracles is a poker run to Benefit the Children's Miracle Network.